Lonafarnib, MedChemExpress

Product Code.	Quantity	unitSize
16496318	10 mg	10mg
16458907	5 mg	5mg

Product Code. 16496318

Brand: Medchem Express HY15136

Description

MedChemExpress Lonafarnib (Sch66336) is a potent and orally active farnesyl transferase (FTase) inhibitor. Lonafarnib inhibits the activities of H-ras, K-ras and N-ras with IC50 values of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Lonafarnib also has anti-hepatitis delta virus (HDV) activities.

Lonafarnib (Sch66336) is a potent and orally active farnesyl transferase (FTase) inhibitor. Lonafarnib inhibits the activities of H-ras, K-ras and N-ras with IC50 values of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Lonafarnib also has anti-hepatitis delta virus (HDV) activities.

Specifications

• Chemical Name or Material: Lonafarnib
• CAS: 193275-84-2
• Color: White
• Purity Grade Notes: Research
• Molecular Formula: C₂₇H₃₁Br₂ClN₄O₂
• Quantity: 10 mg
• Synonym: Sch66336
• Solubility Information: DMSO : 50 mg/mL (78.27 mM; Need ultrasonic)
• SMILES: O=C(N1CCC(CC(N2CCC([C@@H]3C4=C(Br)C=C(Cl)C=C4CCC5=CC(Br)=CN=C53)CC2)=O)CC1)N
• Molecular Weight (g/mol): 638.82
• Formula Weight: 638.82
• Percent Purity: 98.0%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-programmed cell death

Research purposes only