CAS RN 1818339-66-0

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PF-06751979, MedChemExpress

MedChemExpress PF-06751979 is a potent, brain penetrant, β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 7.3 nM in BACE1 binding assay.

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Specifications

Molecular Weight (g/mol)	455.5
Color	White
Physical Form	Solid
Chemical Name or Material	PF-06751979
Grade	Research
SMILES	FC(F)OC1=CN=C(C(NC2=CSC([C@]34CO[C@@H](C)C[C@@]3([H])CSC(N)=N4)=N2)=O)C=C1
For Use With (Application)	Neuroscience-Neurodegeneration
Percent Purity	99.0%
CAS	1818339-66-0
Solubility Information	DMSO : 150 mg/mL (329.31 mM; Need ultrasonic) ∣Ethanol : 50 mg/mL (109.77 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₈H₁₉F₂N₅O₃S₂
Formula Weight	455.5

CAS RN 1818339-66-0

CAS RN 1818339-66-0

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