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PF-06751979, MedChemExpress

Product Code. 16467297
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Product Code. 16467297 Supplier Medchem Express Supplier No. HY112157

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Description

MedChemExpress PF-06751979 is a potent, brain penetrant, β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 7.3 nM in BACE1 binding assay.

PF-06751979 is a potent, brain penetrant, β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 7.3 nM in BACE1 binding assay.

Specifications

Chemical Name or Material PF-06751979
CAS 1818339-66-0
Color White
Purity Grade Notes Research
Molecular Formula C18H19F2N5O3S2
Quantity 5 mg
Solubility Information DMSO : 150 mg/mL (329.31 mM; Need ultrasonic) ∣Ethanol : 50 mg/mL (109.77 mM; Need ultrasonic)
SMILES FC(F)OC1=CN=C(C(NC2=CSC([C@]34CO[C@@H](C)C[C@@]3([H])CSC(N)=N4)=N2)=O)C=C1
Molecular Weight (g/mol) 455.5
Formula Weight 455.5
Percent Purity 99.0%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neurodegeneration
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Research purposes only

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