CAS RN 1654725-02-6

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MedChemExpress GLPG1837 is a potent and reversible CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.

Molecular Weight (g/mol)	348.42
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	GLPG1837
Grade	Research
SMILES	O=C(C1=NNC=C1)NC(S2)=C(C(N)=O)C3=C2C(C)(C)OC(C)(C)C3
Percent Purity	99.03%
CAS	1654725-02-6
Solubility Information	DMSO : ≥ 250 mg/mL (717.52 mM)
Synonym	ABBV-974
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₆H₂₀N₄O₃S
Formula Weight	348.42