CAS RN 1211443-80-9

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Ribociclib hydrochloride, MedChemExpress

MedChemExpress Ribociclib hydrochloride (LEE011 hydrochloride) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.

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Specifications

Molecular Weight (g/mol)	471.0
Color	Yellow
Physical Form	Solid
Chemical Name or Material	Ribociclib hydrochloride
Grade	Research
SMILES	O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(N=C4)=CC=C4N5CCNCC5.Cl
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	99.2%
CAS	1211443-80-9
Solubility Information	H2O : 10 mg/mL (21.23 mM; Need ultrasonic) ∣DMSO : 7.69 mg/mL (16.33 mM; Need ultrasonic)
Synonym	LEE011 hydrochloride
Purity Grade Notes	Research
Recommended Storage	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula	C₂₃H₃₁ClN₈O
Formula Weight	471.0

CAS RN 1211443-80-9

CAS RN 1211443-80-9

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