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Ribociclib hydrochloride, MedChemExpress

Product Code. 16479367
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Product Code. 16479367

Brand: Medchem Express HY15777A

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Description

MedChemExpress Ribociclib hydrochloride (LEE011 hydrochloride) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.

Ribociclib hydrochloride (LEE011 hydrochloride) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.

Specifications

Chemical Name or Material Ribociclib hydrochloride
CAS 1211443-80-9
Color Yellow
Purity Grade Notes Research
Molecular Formula C23H31ClN8O
Quantity 5 mg
Synonym LEE011 hydrochloride
Solubility Information H2O : 10 mg/mL (21.23 mM; Need ultrasonic) ∣DMSO : 7.69 mg/mL (16.33 mM; Need ultrasonic)
SMILES O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(N=C4)=CC=C4N5CCNCC5.Cl
Molecular Weight (g/mol) 471.0
Formula Weight 471.0
Percent Purity 99.2%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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