CAS RN 1127442-82-3

IUPAC Name: 4-{3,5-dioxo-4-azatricyclo[5.2.1.0²,⁶]dec-8-en-4-yl}-N-(quinolin-8-yl)benzamide

Synonyms: 4-{3,5-dioxo-4-azatricyclo[5.2.1.0²,⁶]dec-8-en-4-yl}-N-(quinolin-8-yl)benzamide

Molecular Weight (g/mol): 409.45

Molecular Formula: C25H19N3O3

InChi Key: ZGSXEXBYLJIOGF-UHFFFAOYNA-N

SMILES: O=C(NC1=C2N=CC=CC2=CC=C1)C1=CC=C(C=C1)N1C(=O)C2C3CC(C=C3)C2C1=O

1 – 4 of 4 results

endo-IWR 1 synthesized to Ancillary Material Grade

CAS: 1127442-82-3 Molecular Formula: C25H19N3O3

CAS	1127442-82-3
Molecular Formula	C25H19N3O3

MedChemExpress IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway.

Molecular Weight (g/mol)	409.44
Color	Light Brown
Physical Form	Solid
Chemical Name or Material	IWR-1
Grade	Research
SMILES	O=C(NC1=C2N=CC=CC2=CC=C1)C3=CC=C(N(C([C@]4([H])[C@](C5)([H])C=C[C@]5([H])[C@]64[H])=O)C6=O)C=C3
For Use With (Application)	Cancer-programmed cell death
Percent Purity	97.85%
CAS	1127442-82-3
Solubility Information	DMSO : ≥ 46 mg/mL (112.35 mM)
Health Hazard 1	H302
Synonym	endo-IWR 1 IWR-1-endo
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₅H₁₉N₃O₃
Formula Weight	409.44

WNT pathway inhibitor; AXIN2 stabilizer