Fluorobenzenes

Organic compounds considered aryl halides that consist of a phenyl group with a fluorine atom substitution in the following structure: C₆H₅F.

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Abemaciclib methanesulfonate, MedChemExpress

MedChemExpress Abemaciclib methanesulfonate (LY2835219 methanesulfonate) is a selective CDK4/6 inhibitor with IC50s of 2 nM and 10 nM for CDK4 and CDK6, respectively.

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Specifications

Molecular Weight (g/mol)	602.7
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	Abemaciclib methanesulfonate
Grade	Research
SMILES	CC(N1C2=CC(C3=NC(NC4=NC=C(CN5CCN(CC)CC5)C=C4)=NC=C3F)=CC(F)=C2N=C1C)C.CS(=O)(O)=O
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.0%
CAS	1231930-82-7
Solubility Information	H2O : 125 mg/mL (207.40 mM; Need ultrasonic) ∣DMSO : 10 mg/mL (16.59 mM; ultrasonic and warming and heat to 80°C)
Health Hazard 1	H360∣H373∣H410
Synonym	LY2835219 methanesulfonate
Purity Grade Notes	Research
Recommended Storage	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula	C₂₈H₃₆F₂N₈O₃S
Formula Weight	602.7

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