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Azetidines

Organic heterocyclic compounds that consist of a four-membered ring composed of three carbon atoms, one nitrogen atom, and seven hydrogen atoms.

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1

Carbenicillin disodium, MedChemExpress

MedChemExpress Carbenicillin disodium is a beta-lactam penicillin derivative that interference with final stage of bacterial cell wall synthesis.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 422.36
Color White
Physical Form Solid
Chemical Name or Material Carbenicillin disodium
Grade Research
SMILES O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(C(C(O[Na])=O)C3=CC=CC=C3)=O)N1C2=O)O[Na]
For Use With (Application) COVID-19-immunoregulation
Percent Purity 95.0%
CAS 4800-94-6
Solubility Information H2O : 125 mg/mL (295.96 mM; Need ultrasonic) ∣DMSO : 62.5 mg/mL (147.98 mM; Need ultrasonic)
Health Hazard 1 H317∣H334
Synonym Sodium carbenicillin
Purity Grade Notes Research
Recommended Storage 4°C, sealed storage, away from moisture and light∣The compound is unstable in solutions, freshly prepared is recommended.
Shelf Life 4°C, sealed storage, away from moisture and light∣The compound is unstable in solutions, freshly prepared is recommended.
Molecular Formula C17H16N2Na2O6S
Formula Weight 422.36
2

Baricitinib, MedChemExpress

MedChemExpress Baricitinib (LY3009104; INCB028050) is a selective and orally bioavailable JAK1 and JAK2 inhibitor with IC50s of 5.9 nM and 5.7 nM, respectively.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 371.42
Color White
Physical Form Powder
Chemical Name or Material Baricitinib
Grade Research
SMILES N#CCC1(N2N=CC(C3=C4C(NC=C4)=NC=N3)=C2)CN(S(=O)(CC)=O)C1
For Use With (Application) COVID-19-immunoregulation
Percent Purity 95.0%
CAS 1187594-09-7
Solubility Information DMSO : 25 mg/mL (67.31 mM; Need ultrasonic and warming)
Synonym LY3009104 INCB028050
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C16H17N7O2S
Formula Weight 371.42
3

NSC319726, MedChemExpress

MedChemExpress NSC319726 (ZMC1) is a mutant p53R175 reactivator; inhibits growth of fibroblasts expressing the p53R175 mutation (IC50 = 8 nM); shows no inhibition for p53 wild-type cells.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 234.32
Color Off-White
Physical Form Powder
Chemical Name or Material NSC319726
Grade Research
SMILES C/C(C1=NC=CC=C1)=N\NC(N2CCC2)=S
For Use With (Application) Cancer-programmed cell death
Percent Purity 98.06%
CAS 71555-25-4
Solubility Information DMSO : 31.25 mg/mL (133.36 mM; Need ultrasonic)
Health Hazard 1 H302∣H315∣H319∣H335
Synonym ZMC1
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C11H14N4S
Formula Weight 234.32
4

Ceftazidime, MedChemExpress

MedChemExpress Ceftazidime (GR20263), an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 546.58
Color White
Physical Form Powder
Chemical Name or Material Ceftazidime
Grade Research
SMILES O=C1[C@@H](NC(/C(C2=CSC(N)=N2)=N\OC(C)(C(O)=O)C)=O)[C@@]3([H])SCC(C[N+]4=CC=CC=C4)=C(C([O-])=O)N13
For Use With (Application) COVID-19-immunoregulation
Percent Purity 98.0%
CAS 72558-82-8
Solubility Information H2O : 100 mg/mL (182.96 mM; Need ultrasonic) ∣DMSO : 25 mg/mL (45.74 mM; ultrasonic and warming and heat to 80°C)
Health Hazard 1 H317∣H319∣H334
Synonym GR20263
Purity Grade Notes Research
Recommended Storage 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Shelf Life 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Molecular Formula C22H22N6O7S2
Formula Weight 546.58
5

Enmetazobactam, MedChemExpress

MedChemExpress Enmetazobactam (AAI101) is an extended-spectrum β-lactamase inhibitor, against many resistant Gram-negative pathogens.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 314.32
Color White
Physical Form Solid
Chemical Name or Material Enmetazobactam
Grade Research
SMILES C[N+]1=NN(C[C@@](S([C@]2([H])C3)(=O)=O)(C)[C@H](C([O-])=O)N2C3=O)C=C1
For Use With (Application) COVID-19-immunoregulation
Percent Purity 95.0%
CAS 1001404-83-6
Solubility Information DMSO : ≥ 113.3 mg/mL (360.46 mM)
Health Hazard 1 H315∣H317∣H318∣H334∣H335∣H341∣H361∣H370∣H413
Synonym AAI101
Purity Grade Notes Research
Recommended Storage -20°C, protect from light, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light, stored under nitrogen)
Shelf Life -20°C, protect from light, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light, stored under nitrogen)
Molecular Formula C11H14N4O5S
Formula Weight 314.32