Azepanes
Organic heterocyclic compounds that consist of a seven-membered ring composed of six carbon atoms, one nitrogen atom, and thirteen hydrogen atoms; these compounds are cyclic secondary amines.
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ANA-12, MedChemExpress
MedChemExpress ANA-12 is a potent and selective TrkB antagonist with IC50s of 45.6 nM and 41.1 μM for the high and low affinity sites, respectively.
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Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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| Molecular Weight (g/mol) | 407.49 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | ANA-12 |
| Grade | Research |
| SMILES | O=C(C1=CC2=CC=CC=C2S1)NC3=CC=CC=C3C(NC4C(NCCCC4)=O)=O |
| For Use With (Application) | Neuroscience-Neuromodulation |
| Percent Purity | 99.3% |
| CAS | 219766-25-3 |
| Solubility Information | DMSO : 9.09 mg/mL (22.31 mM; Need ultrasonic) ∣Ethanol : < 1 mg/mL (ultrasonic) (insoluble) |
| Health Hazard 1 | H302 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C22H21N3O3S |
| Formula Weight | 407.49 |
Brepocitinib P-Tosylate, MedChemExpress
MedChemExpress Brepocitinib (PF-06700841) P-Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. Brepocitinib P-Tosylate also inhibits JAK2 and JAK3 with IC50s of 77 nM and 6.49 μM, respectively.
Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
| Molecular Weight (g/mol) | 561.6 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Brepocitinib P-Tosylate |
| Grade | Research |
| SMILES | O=C([C@H]1C(F)(F)C1)N2C3CN(C4=NC(NC5=CN(C)N=C5)=NC=C4)CC2CC3.O=S(C6=CC=C(C)C=C6)(O)=O |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 99.69% |
| CAS | 2140301-96-6 |
| Solubility Information | DMSO : 62.5 mg/mL (111.29 mM; Need ultrasonic) |
| Synonym | PF-06700841 P-Tosylate |
| Purity Grade Notes | Research |
| Recommended Storage | 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture) |
| Shelf Life | 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture) |
| Molecular Formula | C25H29F2N7O4S |
| Formula Weight | 561.6 |