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Acrylic acids and derivatives

Organic compounds that consist of a carboxylic acid with a vinyl functional group substitution; vinyl functional groups are a carbon - carbon double bond. Includes compounds that are derived from acrylic acids.

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1

7ACC1, MedChemExpress

MedChemExpress 7ACC1(DEAC; Coumarin D 1421; D 1421) selectively interfere with lactate fluxes in the lactate-rich tumor microenvironment; inhibits lactate influx but not efflux in tumor cells expressing MCT1 and MCT4 transporters.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 261.27
Color Orange
Physical Form Solid
Chemical Name or Material 7ACC1
Grade Research
SMILES O=C(C1=CC2=CC=C(N(CC)CC)C=C2OC1=O)O
For Use With (Application) Cancer-programmed cell death
Percent Purity 99.96%
CAS 50995-74-9
Solubility Information DMSO : 33.33 mg/mL (127.57 mM; Need ultrasonic)
Health Hazard 1 H302∣H315∣H319∣H335
Synonym DEAC Coumarin D 1421 D 1421
Purity Grade Notes Research
Recommended Storage 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Shelf Life 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Molecular Formula C14H15NO4
Formula Weight 261.27
2

Praeruptorin B, MedChemExpress

MedChemExpress Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs).

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 426.46
Color White
Physical Form Powder
Chemical Name or Material Praeruptorin B
Grade Research
SMILES O=C1C=CC2=CC=C3C([C@H](OC(/C(C)=C\C)=O)[C@H](OC(/C(C)=C\C)=O)C(C)(C)O3)=C2O1
For Use With (Application) Metabolism-sugar/lipid metabolism
Percent Purity 99.88%
CAS 73069-28-0
Solubility Information DMSO : 25 mg/mL (58.62 mM; ultrasonic and warming and heat to 60°C)
Synonym Praeruptorin D
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C24H26O7
Formula Weight 426.46
3

Vicriviroc maleate, MedChemExpress

MedChemExpress Vicriviroc maleate (SCH-417690 maleate; SCH-D maleate) is a potent, selective, oral bioavailable and CNS penetrated antagonist of CCR5, with a Ki of 2.5 nM, and also inhibits HIV-1 in PBMC cells, with IC90s of 3.3 nM (JrFL), 2.8 nM (ADA-M), 1.8 nM (301657), 4.9 nM (JV1083) and 10 nM (RU 570).

ENCOMPASS_PREFERRED