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Invitrogen™ ZSCAN4 Polyclonal Antibody

Product Code. 12829042 Shop All Thermo Scientific Products
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Quantity:
100 μg
Unit Size:
100µg
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12829042 100 μg 100µg
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Product Code. 12829042 Supplier Invitrogen™ Supplier No. PA520901

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Description

Rabbit Polyclonal Antibody

A suggested positive control is mouse lung tissue lysate. PA5-20901 can be used with blocking peptide PEP-1015.

Zytotic genome activation (ZGA) is the first and most critical transition event from the maternal genetic to the embryonic genetic program and the major burst of ZGA occurs only in the late 2-cell stage. ZSCAN4 encodes a SCAN domain and four zinc finger domains and is expressed in late 2-cell embryos and embryonic stem cells. Loss-of-function studies using siRNA shows delays in the progression from the 2-cell to the 4-cell stage and subsequent embryo development. ZSCAN4 plays an important role in the preimplantation development. Also, ZSCAN4 is involved in telomere maintenance and long term genomic stability in ES cells, suggesting that ZSCAN4 may be of critical importance in maintaining pluripotency in replicating stem cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZSCAN4
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ZSCAN4
Gene Accession No. Q3URS2, Q8NAM6
Gene Alias BQ559217; C330039H09Rik; RGD1563625; zinc finger and SCAN domain containing 4; zinc finger and SCAN domain containing 4A; zinc finger and SCAN domain containing 4F; zinc finger and SCAN domain containing protein 4F; Zinc finger and SCAN domain-containing protein 4; zinc finger protein 494; ZNF494; ZSCAN4; Zscan4a; Zscan4f
Gene Symbols ZSCAN4, Zscan4a, Zscan4f
Host Species Rabbit
Immunogen An 18 amino acid peptide near the carboxy terminus of human ZSCAN4.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 201516, 434555, 503124, 665902
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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