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Invitrogen™ ZRANB2 Polyclonal Antibody
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Product Code. 15507541
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Quantity:
100 μL
Unit Size:
100µL
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15507541 100 μL 100µL
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Product Code. 15507541 Supplier Invitrogen™ Supplier No. PA536139

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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 37 kDa. Purity is >95% by SDS-PAGE.

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF265 (Zinc finger protein 265), also known as ZRANB2 (Zinc finger Ran-binding domain-containing protein 2), ZIS, ZIS1 or ZIS2, is a 330 amino acid protein that belongs to the ZRANB2 family. Localized to the nucleus, ZNF265 functions as a splicing factor that is responsible for alternatively splicing Tra-2 beta (transformer-2 beta) transcripts and is thought to interfere with constitutive 5'-splice selection. ZNF265 contains two RanBP2-type zinc fingers through which it conveys its RNA-binding activity. Two isoforms, designated ZIS-1 and ZIS-2, are expressed due to alternative splicing events. Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZRANB2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Zranb2
Gene Accession No. O35986, O95218, Q9R020
Gene Alias AI227013; DKFZp686J1831; DKFZp686N09117; wu:fa96h03; Zfp265; zgc:56597; zinc finger protein 265; Zinc finger Ran-binding domain-containing protein 2; Zinc finger Ran-binding domain-containing protein 2-like protein; zinc finger RANBP2-type containing 2; zinc finger, RAN-binding domain containing 2; zinc finger, splicing; zinc-finger protein 265; zinc-finger, splicing; ZIS; ZIS1; ZIS2; Znf265; ZRANB2
Gene Symbols Zranb2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 121-170 of human ZIS.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 53861, 58821, 9406
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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