ZNF174 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16838214	Proteintech 18157-1-AP-20UL	20 μL
16828214	Proteintech 18157-1-AP-150UL	150 μL

Description

ZNF174, also known as ZSCAN8 or AW-1, is a transcriptional repressor that belongs to the Krueppel C2H2-type zinc-finger protein family. It is expressed in a number of different tissues, including small intestine, prostate, colon, spleen, pancreas, skeletal muscle, brain, heart, kidney and thymus, but it is most predomitly found in adult ovary and testis. ZNF174 specifically acts to repress the promoter activities of PDGF-B and TGF beta1. ZNF174 localizes to the nucleus and contains three C2H2-type zinc fingers at the C-terminus and one SCAN domain near the N-terminus. SCAN domains are found in a number of zinc-finger proteins and are characterized by a conserved region of 84 residues. The SCAN domain seemingly regulates the association of proteins containing SCAN domains into noncovalent complexes and may also function as an underlying mechanism in selective oligomerization of these proteins.

Specifications

• Antigen: ZNF174
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: Q15697
• Gene ID (Entrez): 7727
• Immunogen: ZNF174 Fusion Protein Ag12963
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: ZNF174

• Concentration: 0.28 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: AW 1, zinc finger protein 174, ZNF174, ZSCAN8
• Gene Symbols: ZNF174
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody