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Invitrogen™ ZMIZ2 Polyclonal Antibody

Description
Recommended positive controls: IMR32. Predicted reactivity: Mouse (92%), Rat (93%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.
Specifications
Specifications
| Antigen | ZMIZ2 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 0.93 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7 |
| Gene | ZMIZ2 |
| Gene Accession No. | Q8NF64 |
| Gene Alias | D11Bwg0280e; HRIHFB2007; hZIMP7; KIAA1886; NET27; PIAS-like protein Zimp7; TRAFIP20; Zimp7; zinc finger MIZ domain-containing protein 2; zinc finger MIZ-type containing 2; zinc finger, MIZ-type containing 2; Zmiz2 |
| Gene Symbols | ZMIZ2 |
| Show More |
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