Invitrogen™ ZIPK Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA597654

Product Code. 16570482

Description

ZIPK Polyclonal Antibody for Western Blot, ICC/IF, ELISA

DAPK3 is a serine/threonine kinase which is functionally linked to cell motility, smooth muscle contractility and cell death processes. DAPK3 is encoded by ZIPK and is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.

Specifications

• Antigen: ZIPK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DAPK3
• Gene Alias: DAP kinase 3; DAP3K; Dapk3; Dapkl; DAP-like kinase; death associated protein kinase 3; death-associated kinase 3; Death-associated like kinase; death-associated protein kinase 3; DLK; MYPT1 kinase; ZIP; ZIP kinase; ZIP kinase isoform; Zipk; ZIP-kinase; zipper-interacting protein kinase
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 1613
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 5 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: O43293
• Gene Symbols: DAPK3
• Immunogen: Recombinant Human Death-associated protein kinase 3 protein (283-401AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG