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Invitrogen™ ZHX2 Recombinant Mouse Monoclonal Antibody (K94050_5A8)
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Product Code. 30827841
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Product Code. 30827841 Supplier Invitrogen™ Supplier No. MA564451

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Mouse Recombinant Monoclonal Antibody

Immunogen sequence: QDVPEEVDRA KEKGIGTPQP DVAKDSWAAE LENSSKENEV IEVKSMGESQ SKKLQGGYEC KYCPYSTQNL NEFTEHVDMQ HPNVILNPLY VCAECNFTTK KYDSLSDHNS KFHPGEANFK LKLIKRNNQT VLEQSIETTN HVVSITTSGP Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 85%, Pig - 90%, Cynomolgus monkey - 98%.

Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys(2)-His(2)-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZHX2
Applications Immunohistochemistry (Paraffin)
Classification Recombinant Monoclonal
Clone K94050_5A8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.5% BSA, 50% glycerol and 0.09% sodium azide
Gene ZHX2
Gene Accession No. Q9Y6X8
Gene Alias AFP regulator 1; AFR1; Afr-1; alpha fetoprotein regulation 1, adult; alpha-fetoprotein regulator 1; KIAA0854; LOW QUALITY PROTEIN: zinc fingers and homeoboxes protein 2; mKIAA0854; Raf; Regulator of AFP; transcription factor ZHX2; Zhx2; Zinc finger and homeodomain protein 2; zinc fingers and homeoboxes 2; zinc fingers and homeoboxes protein 2; zinc-fingers and homeoboxes 2
Gene Symbols ZHX2
Host Species Mouse
Immunogen Recombinant human ZHX2 (aa 21-170).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22882
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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