Invitrogen™ ZFYVE27 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA590842

Product Code. 16538021

Description

Immunogen sequence: VEFFRVVSEY RASLQQRMNP KQEEHAFESP PPPDVGGKDG LMDSTPALTP TEDLTPGSVE EAEEAEPDEE FKDAIEETHL VVLEDDEGAP CPAEDELALQ DNGFLSKNEV LRSKVSRLTE RLRKRYPTNN FGNCTGCSAT FSVLKKRRSC SNCGNSFCSR CCSFKVPKSS MGATAPEAQR ETVFVCASCN QTLSK; Positive Samples: Rat eye; Cellular Location: Cell membrane, Cell projection, Endoplasmic reticulum membrane, Multi-pass membrane protein, Recycling endosome membrane, growth cone membrane.

This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.

Specifications

• Antigen: ZFYVE27
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZFYVE27
• Gene Alias: 2210011N02Rik; 9530077C24Rik; AI426636; AI593546; AI835681; im:7137347; LOW QUALITY PROTEIN: protrudin; PROTRUDIN; RP11-459F3.2; Spastic paraplegia 33 protein; SPG33; zfyve27; zgc:153156; zinc finger FYVE domain containing 27; zinc finger FYVE domain-containing protein 27; zinc finger FYVE-type containing 27; zinc finger, FYVE domain containing 27; zinc finger, FYVE domain containing 27 isoform c
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 118813, 309376
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.22 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q5T4F4, Q6P7B7
• Gene Symbols: ZFYVE27
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 217-411 of human ZFYVE27 (NP_6531893).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG