Invitrogen™ ZFHX3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5119848

Product Code. 17701254

Descripción

Positive Control: Rat esophagus tissue, human colon tissue, human breast carcinoma tissue, human stomach carcinoma tissue. Subcellular Location: Nucleus, Cytoplasm. Western Blot: 1:500 for endogenous lysates (predicted); 1:5,000 for recombinant protein.

Transcriptional repressor. It inhibits the enhancer element of the AFP gene by binding to its AT-rich core sequence. Regulator of myoblasts differentiation through the binding to the AT-rich sequence of MYF6 promoter and promoter repression. Down-regulates the MUC5AC promoter in gastric cancer. Miura Y., J. Biol. Chem. 270:26840-26848(1995). Morinaga T., Mol. Cell. Biol. 11:6041-6049(1991). Martin J., Nature 432:988-994(2004).

Especificaciones

• Antigen: ZFHX3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZFHX3
• Gene Alias: A230102L03Rik; alpha-fetoprotein enhancer binding protein; alpha-fetoprotein enhancer-binding protein; AT motif binding factor 1; AT motif-binding factor 1; ATBF1; AT-binding transcription factor 1; ATBT; C16orf47; mKIAA4228; Putative uncharacterized protein C16orf47; RGD1560268; WBP9; ZFH-3; Zfhx3; zinc finger homeobox 3; zinc finger homeobox protein 3; Zinc finger homeodomain protein 3; ZNF927
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 307829, 463
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q15911
• Gene Symbols: ZFHX3
• Immunogen: Recombinant protein within human ATBF1 aa 1,800-2,000.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG