Invitrogen™ ZC3H8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA521811

Product Code. 13299828

Description

Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Zinc-finger CCCH domain-containing protein 8 (ZC3H8) acts as a transcriptional repressor of the GATA3 promoter. It is a sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene. ZC3H8 induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

Specifications

• Antigen: ZC3H8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZC3H8
• Gene Alias: AU020882; E130108N08Rik; fetal liver zinc finger 1; fetal liver zinc finger 1; putative zinc finger protein FLIZ1; fetal liver zinc finger protein 1; Fliz1; ZC3H8; Zc3hdc8; zinc finger CCCH domain-containing protein 8; zinc finger CCCH type containing 8; zinc finger CCCH type domain containing 8; zinc finger CCCH-type containing 8; zinc finger CCCH-type domain containing 8
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84524
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.84 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8N5P1
• Gene Symbols: ZC3H8
• Immunogen: Recombinant protein encompassing a sequence within the center region of human ZC3H8. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG