Invitrogen™ ZC3H12D Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5110590

Product Code. 17168513

Description

Immunogen sequence: QHVLAELERQ AVLVYTPSRK VHGKRLVCYD DRYIVKVAYE QDGVIVSNDN YRDLQSENPE WKWFIEQRLL MFSFVNDRFM P.

ZC3H12D, also known as MCPIP4, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. ZC3H12D is highly expressed in spleen, intestine, and colon. Similar to ZC3H12A and ZC3H12C, ZC3H12D expression in murine macrophages is also increased after treatment with lipopolysaccharide (LPS), although not to the same level as ZC3H12A. This pattern of expression was not duplicated in human-derived macrophages, suggesting it also may play a different role in host immunity and inflammatory response.

Specifications

• Antigen: ZC3H12D
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZC3H12D
• Gene Alias: C6orf95; D730019B10Rik; dJ281H8.1; MCP-induced protein 4; MCPIP4; p34; probable ribonuclease ZC3H12D; RP1-281H8.5; Tfl; Transformed follicular lymphoma; transformed follicular lymphoma homolog; tumor suppressor TFL; zc3h12d; Zinc finger CCCH domain-containing protein 12D; zinc finger CCCH type containing 12D; zinc finger CCCH-type containing 12D
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 237256, 308266, 340152
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.50 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: A2A288, Q8BIY3
• Gene Symbols: ZC3H12D
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 150-230 of human ZC3H12D (NP_997243.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG