Invitrogen™ ZBTB8A Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA568525

Product Code. 15896933

Description

This target displays homology in the following species: Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 100%.

The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB8, also known as BOZ-F1, is present in multiple tissues, and is highly expressed in the cytoplasm of the placenta. While little is known about ZBTB8, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB proteins, ZBTB7A, has been implicated as a proto-oncogene whose overexpression contributes to malignancy in breast cancer, suggesting that ZBTB8 may act as a transcriptional repressor or be involved in tumorigenesis.

Specifications

• Antigen: ZBTB8A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZBTB8A
• Gene Alias: 2410081M15Rik; AI480941; BOZF1; BOZ-F1; BTB/POZ and zinc-finger domain-containing factor; BTB/POZ and zinc-finger domains factor on chromosome 1; ZBTB8; Zbtb8a; zinc finger and BTB domain containing 8; zinc finger and BTB domain containing 8a; zinc finger and BTB domain-containing protein 8A; ZNF916A
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 653121
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q96BR9
• Gene Symbols: ZBTB8A
• Immunogen: synthetic peptide directed towards the c terminal region of human ZBTB8A.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG