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  6. YTHDF2 Rabbit anti-Human, Polyclonal, Proteintech

YTHDF2 Rabbit anti-Human, Polyclonal, Proteintech

Product Code. 16843235 Shop All Proteintech Products
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20 μL
150 μL
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150µL
20µL
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16843235 20 μL 20µL
16833235 150 μL 150µL
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Product Code. 16843235 Supplier Proteintech Supplier No. 247441AP20UL

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Description

Rabbit Polyclonal Antibody

Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation. Also acts as a promoter of cap-independent mRNA translation following heat shock stress: upon stress, relocalizes to the nucleus and specifically binds mRNAs with some m6A methylation mark at their 5′-UTR, protecting demethylation of mRNAs by FTO, thereby promoting cap-independent mRNA translation.

Specifications

Antigen YTHDF2
Applications Immunohistochemistry (Paraffin), Immunocytochemistry, Immunoprecipitation, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene YTHDF2
Gene Accession No. Q9Y5A9
Gene Alias CLL associated antigen KW 14, HGRG8, NY REN 2, YTH domain family protein 2, YTH domain family, member 2, YTHDF2
Gene Symbols YTHDF2
Host Species Rabbit
Immunogen YTHDF2 Fusion Protein Ag5922
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51441
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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