Invitrogen™ YPEL5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA534351

Product Code. 15385271

Description

A suggested positive control is A-20 cell lysate. PA5-34351 can be used with blocking peptide PEP-1394.

YPEL5 (yippee-like 5) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL5 is expressed at the nucleus and centrosome during interphase; during mitosis, it localizes to the spindle poles, mitotic spindle, and spindle midzone during mitosis. Finally, during cytokinesis, YPEL5 is localized to the midbody. It is associated with the Ran Binding Protein in the Microtubule organizing center (RanBPM) and a related protein RanBP10.

Specifications

• Antigen: YPEL5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ypel5
• Gene Alias: 2310076K21Rik; CGI-127; Protein yippee-like 5; yippee like 5; yippee protein homolog; yippee-like 5; yippee-like 5 (Drosophila); Ypel5
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 383295, 51646
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P62699, P62700
• Gene Symbols: Ypel5
• Immunogen: A 14 amino acid synthetic peptide near the amino terminus of human YPEL5.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG