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Yoda 1, MedChemExpress

Product Code. p-200100531
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Product Code. 16490078

Brand: Medchem Express HY18723

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Description

MedChemExpress Yoda 1 is a potent and selective Piezo1 agonist. Yoda 1 activates purified Piezo1 channels. Yoda1 induces activation of both Akt and ERK1/2 in endothelial cells (ECs), which is not dependent on Piezo1. Yoda 1 potently inhibits macropinocytosis induced by epidermal growth factor (EGF). Yoda 1 enhances Ca2+ influx followed by activation of the calcium-activated potassium channel KCa3.1 and inhibition of Rac1 activation.

Yoda 1 is a potent and selective Piezo1 agonist. Yoda 1 activates purified Piezo1 channels. Yoda1 induces activation of both Akt and ERK1/2 in endothelial cells (ECs), which is not dependent on Piezo1. Yoda 1 potently inhibits macropinocytosis induced by epidermal growth factor (EGF). Yoda 1 enhances Ca2+ influx followed by activation of the calcium-activated potassium channel KCa3.1 and inhibition of Rac1 activation.

Specifications

Chemical Name or Material Yoda 1
Physical Form Powder
CAS 448947-81-7
Color White
Quantity 5 mg
Purity Grade Notes Research
Molecular Formula C13H8Cl2N4S2
For Use With (Application) COVID-19-immunoregulation
Solubility Information DMSO : 15.62 mg/mL (43.97 mM; ultrasonic and warming and heat to 60°C)
SMILES ClC1=C(CSC2=NN=C(C3=NC=CN=C3)S2)C(Cl)=CC=C1
Molecular Weight (g/mol) 355.27
Formula Weight 355.27
Percent Purity 99.83%
Grade Research
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Research purposes only

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