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  7. Y-27632 dihydrochloride, MedChemExpress

Y-27632 dihydrochloride, MedChemExpress

Product Code. 16486757
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Product Code. 16486757

Brand: Medchem Express HY10583

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Description

MedChemExpress Y-27632 dihydrochloride is an orally active, ATP-competitive inhibitor of ROCK-I and ROCK-II, with Kis of 220 and 300 nM, respectively.

Y-27632 dihydrochloride attenuates Doxorubicin-induced apoptosis of human cardiac stem cells. Y-27632 also suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells. Y-27632 dihydrochloride primes human induced pluripotent stem cells (hIPSCs) to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation.

Specifications

Chemical Name or Material Y-27632 dihydrochloride
CAS 129830-38-2
Color White
Purity Grade Notes Research
Molecular Formula C14H23Cl2N3O
Quantity 5 mg
Solubility Information H2O : 100 mg/mL (312.25 mM; Need ultrasonic) ∣DMSO : 33.33 mg/mL (104.07 mM; Need ultrasonic)
SMILES O=C([C@@H]1CC[C@]([C@H](N)C)([H])CC1)NC2=CC=NC=C2.[H]Cl.[H]Cl
Molecular Weight (g/mol) 320.26
Formula Weight 320.26
Percent Purity 95.0%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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