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Tocris Bioscience™ XMD 8-92
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Product Code. 18084252
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Product Code. Quantity unitSize
18084252 10 mg 10mg
18055102 50 mg 50mg
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Product Code. 18084252

Brand: Tocris Bioscience™ 4132/10

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222.70 GBP valid until 2026-03-31
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This item is not returnable. View return policy

Description

ERK5/BMK1 inhibitor; also BRD4 inhibitor

ERK5 (BMK1) and BRD4 inhibitor (Kd values are 80 and 190 nM, respectively). Also inhibits DCAMKL2, PLK4 and TNK1 (Kd values are 190, 600 and 890 nM). Blocks growth factor-induced activation of cellular BMK1 and reduces BMK1 activity in in vitro kinase assays. Also reduces BMK1-dependent transactivating activity of MEF2C. Inhibits proliferation in a variety of cancer cell lines; blocks tumor cell proliferation and tumor-associated angiogenesis.
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Chemical Identifiers

CAS 1234480-50-2
Molecular Formula C26H30N6O3

Specifications

Quantity 10 mg
Formula Weight 474.55
Purity >98%
Molecular Weight (g/mol) 474.565
Chemical Name or Material XMD 8-92
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