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Tocris Bioscience™ XE 991 dihydrochloride

Product Code. 30001293
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50 mg
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30001293 10 mg 10mg
18024722 50 mg 50mg
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Product Code. 30001293 Supplier Tocris Bioscience™ Supplier No. 2000/10

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Description

Potent, selective KV7 (KCNQ) channel blocker; blocks M-currents

Potent and selective blocker of KV7 (KCNQ) voltage-gated potassium channels. Blocks KV7.2+7.3 (KCNQ2+3)/ M-currents (IC50 = 0.6 - 0.98 μM) and KV7.1 (KCNQ1) homomeric channels (IC50 = 0.75 μM) but is less potent against KV7.1/minK channels (IC50 = 11.1 μM). Augments hippocampal ACh release and is a cognitive enhancer following oral administration in vivo.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 122955-13-9
Molecular Formula C26H22Cl2N2O

Specifications

Quantity 10 mg
Formula Weight 449.37
Purity >99%
Molecular Weight (g/mol) 449.375
Chemical Name or Material XE 991 dihydrochloride
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