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  6. Invitrogen™ WWOX Recombinant Rabbit Monoclonal Antibody (K01_2Q01)

Invitrogen™ WWOX Recombinant Rabbit Monoclonal Antibody (K01_2Q01)
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Product Code. 30829288
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100 μL
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30829288 100 μL 100µL
30828144 50 μL -
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Product Code. 30829288 Supplier Invitrogen™ Supplier No. MA564238

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Description

Rabbit Recombinant Monoclonal Antibody

WWOX Recombinant Monoclonal Antibody for IHC (P), Western Blot

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen WWOX
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone K01_2Q01
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 0.05% BSA, 150mM NaCl, 40% glycerol and 0.01% sodium azide; pH 7.4
Gene Wwox
Gene Accession No. Q91WL8, Q9NZC7
Gene Alias 5330426P09Rik; 9030416C10Rik; D16S432E; EIEE28; FOR; FRA16D; Fragile site FRA16D oxidoreductase; HHCMA56; PRO0128; SCAR12; SDR41C1; Short chain dehydrogenase/reductase family 41C member 1; short chain dehydrogenase/reductase family 41C, member 1; WOX1; WW domain containing oxidoreductase; WW domain-containing oxidoreductase; WW domain-containing protein WWOX; WW-domain oxidoreductase; Wwox
Gene Symbols Wwox
Host Species Rabbit
Immunogen Recombinant protein of human WWOX.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51741, 80707
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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