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Invitrogen™ WT1 Polyclonal Antibody
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Product Code. 11366523
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100 μg
Unit Size:
100µg
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11366523 100 μg 100µg
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Product Code. 11366523 Supplier Invitrogen™ Supplier No. PA518548

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Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

The Wilms Tumor 1 gene encodes one of the WPP domain-interacting proteins (Wilms Tumor 1/AT5G11390, WIT2/AT1G68910) required for RanGAP nuclear envelope association in root tip cells. Ran GTPase plays essential roles in multiple cellular processes, including nucleocytoplasmic transport, spindle formation, and postmitotic nuclear envelope reassembly. The cytoplasmic Ran GTPase activating protein RanGAP is critical to establish a functional RanGTP/RanGDP gradient across the nuclear envelope and is associated with the outer surface of the nuclear envelope in metazoan and higher plant cells. Arabidopsis thaliana RanGAP association with the root tip nuclear envelope requires a family of likely plant-specific nucleoporins combining coiled-coil and transmembrane domains (CC-TMD) and WPP domain-interacting proteins (WIPs). Wilms Tumor 1 and WIT2 have been identified as a second family of CC-TMD proteins, structurally similar, yet clearly distinct from the WIP family, that is required for RanGAP nuclear envelop association in root tip cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen WT1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene WT1
Gene Accession No. P19544
Gene Alias AWT1; D630046I19Rik; EWS-WT1; GUD; NPHS4; WAGR; Wilms tumor 1; Wilms tumor 1 homolog; Wilms tumor protein; Wilms tumor protein homolog; Wilms tumor protein isoform Ex4a(+); WIT1; WIT-1; WIT-2; WT; Wt1; Wt-1; WT1 antisense RNA; WT1AS; WT1-AS; WT1-AS1; WT33
Gene Symbols WT1
Host Species Goat
Immunogen Synthetic peptide sequence (QDPASTCVPEPASQH) corresponding to the N-terminus amino acids of WT1 (aa 7-21).
Purification Method Ammonium Sulfate Precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7490
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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