WT1 Mouse anti-Human, Clone:5G11A5, Abnova™

Mouse monoclonal antibody raised against recombinant human WT1.

Brand:  Abnova MAB16633.100ug

Product Code. 16094406

Description

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm′s tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq]

Specifications

• Antigen: WT1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Flow Cytometry (1:200-1:400)
  The optimal working dilution should be determined by the end user.
• Gene: WT1
• Host Species: Mouse
• Quantity: 100 μg
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: 5G11A5
• Description: Wilms tumor 1
• Formulation: In PBS (0.05% sodium azide)
• Gene Alias: GUD, WAGR, WIT-2, WT33
• Immunogen: Recombinant protein corresponding to amino acid 314-479 of human WT1 from E. coli.
• Gene ID (Entrez): 7490
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid