WT1 Antibody (SPM361) - IHC-Prediluted, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-48215

Product Code. 18154168

Description

WT1 Monoclonal specifically detects WT1 in Human, Rat samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: WT1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: 1.0mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Symbols: WT1
• Immunogen: Recombinant protein corresponding to residues 1-181 of human WT1. (Uniprot: P19544)
• Quantity: 7 mL
• Research Discipline: Angiogenesis, Cancer, Cell Cycle and Replication, Cellular Markers, Chromatin Research, Tumor Suppressors
• Gene ID (Entrez): 7490
• Target Species: Human, Mouse
• Form: Purified

• Applications: Immunohistochemistry (Paraffin)
• Clone: SPM361
• Dilution: Immunohistochemistry-Paraffin
• Gene Alias: AWT1, NPHS4GUD, WAGR, Wilms tumor 1, Wilms tumor protein, WIT-2, WT33
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes a 47-55kDa-tumor suppressor protein, identified as Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ