Invitrogen™ WSB1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA570550

Product Code. 15808963

Description

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 100%.

WSB1 (WD repeat and SOCS box-containing 1), also known as SWIP1, is a 421 amino acid protein that contains one SOCS box domain and six WD repeats. Expressed as multiple alternatively spliced isoforms, WSB1 is thought to function as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates the ubiquitination and proteasomal degradation of target proteins, such as DIO2. Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role for WSB1 in carcinogenesis.

Specifications

• Antigen: WSB1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WSB1
• Gene Alias: 1110056B13Rik; 2700038M07Rik; SOCS box-containing WD protein SWiP-1; SWIP1; WD repeat and SOCS box containing 1; WD repeat and SOCS box-containing 1; WD repeat and SOCS box-containing protein 1; WD repeat and SOCS box-containing protein 1-like protein; WD-40-repeat-containing protein with a SOCS box 1; WSB1; WSB-1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 303336
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: 0
• Gene Symbols: WSB1
• Immunogen: synthetic peptide directed towards the middle region of rat WSB1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG