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Invitrogen™ WNT10A Polyclonal Antibody

Product Code. 12818722
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Quantity:
100 μg
Unit Size:
100µg
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12818722 100 μg 100µg
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Product Code. 12818722 Supplier Invitrogen™ Supplier No. PA520542

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Description

Rabbit Polyclonal Antibody

A suggested positive control is RAW264.7 cell lysate. PA5-20542 can be used with blocking peptide PEP-0662. This Wnt10a antibody is predicted to not cross-react with Wnt10b.

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region.
TRUSTED_SUSTAINABILITY

Specifications

Antigen WNT10A
Applications Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene WNT10A
Gene Accession No. P70701, Q9GZT5
Gene Alias OODD; Protein Wnt-10a; SSPS; STHAG4; wingless related MMTV integration site 10a; wingless-type MMTV integration site family member 10A; wingless-type MMTV integration site family, member 10A; Wnt family member 10A; Wnt10a
Gene Symbols WNT10A
Host Species Rabbit
Immunogen A 14 amino acid synthetic peptide from near the carboxy terminus of human Wnt10a. The immunogen is located within amino acids 300-350 of Wnt10a.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22409, 316527, 80326
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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