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Invitrogen™ West Nile Virus Core Antigen Polyclonal Antibody

Product Code. 12818342
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Quantity:
100 μg
Unit Size:
100µg
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12818342 100 μg 100µg
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Product Code. 12818342 Supplier Invitrogen™ Supplier No. PA520103

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Description

Rabbit Polyclonal Antibody

PA5-20103 can be used with blocking peptide PEP-0221.

West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins which play a major role for WNV entry into target cells. The viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway as delivery of core gene delivery into the striatum of mouse brain and skeletal muscle resulted in cell death and inflammation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen West Nile Virus Core Antigen
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Alias West Nile Core; WNV core
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 15 amino acids near the carboxy terminus of the West Nile Virus core protein.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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