WEE2 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16876575	Proteintech 55119-1-AP-20UL	20 μL
16866575	Proteintech 55119-1-AP-150UL	150 μL

Description

The antibody is specific to WEE2.

Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at ′Tyr-15′, leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at ′Tyr-15′, to ensure exit from meiosis in oocytes and promote pronuclear formation.

Specifications

• Antigen: WEE2
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: P0C1S8
• Gene ID (Entrez): 494551
• Immunogen: Peptide
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: WEE2

• Concentration: 0.47 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: 0.1 M glycine, 0.1 M sodium bicarbonate with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: WEE1 homolog 2 (S. pombe), Wee1 like protein kinase 1B, Wee1 like protein kinase 2, WEE1B, Wee1B kinase, WEE2
• Gene Symbols: WEE2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody