Invitrogen™ WDR92 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA557236

Product Code. 15775131

Description

Immunogen sequence: GVIQLYEIQH GDLKLLREIE KAKPIKCGTF GATSLQQRYL ATGDFGGNLH IWNLEAPEMP VYSVKGHKEI INAIDGIGGL GIGEGAPEIV Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 92%.

WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR92, also known as monad, contains two WD40 repeats is widely expressed in human tissues, especially testis. Overexpression of this protein or its binding partner RNA polymerase II-associated protein 3 (RPAP3) potentiated apoptosis and caspase-3 activation induced by TNF-a and cycloheximide, suggesting that WDR92, together with RPAP3, may function as a novel modulator of apoptosis.

Specifications

• Antigen: WDR92
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WDR92
• Gene Alias: AI553587; HZGJ; monad; RGD1563863; testicular secretory protein Li 67; WD repeat domain 92; WD repeat-containing protein 92; WD repeat-containing protein Monad; Wdr92
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 103784, 116143, 498418
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8BGF3, Q96MX6
• Gene Symbols: WDR92
• Immunogen: Recombinant protein corresponding to Human WDR92. Recombinant protein control fragment (Product #RP-96033).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG