WDR74 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA520924

Product Code. 12829072

Description

A suggested positive control is mouse liver tissue lysate. PA5-20924 can be used with blocking peptide PEP-1038.

The yeast nucleolar protein NOP7 is necessary for the maturation of 66S preribosomes and interacts with numerous other proteins. One such protein is an essential, conserved WD repeat protein, NOP seven-associated protein 1 (NSA1), that is also required for the yeast 66S ribosome assembly. NSA1 is also associated with the AAA ATPase Rix7, and release of NSA1 from a novel late nucleolar pre-60S requires the Rix7 function. NSA1 has also been found upregulated in mammalian cancer cells, suggesting it may also play a role in cell proliferation.

Specifications

• Antigen: WDR74
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WDR74
• Gene Alias: 5730436H21Rik; AA407588; NOP seven-associated protein 1; NSA1; WD repeat domain 74; WD repeat-containing protein 74; Wdr74
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 107071, 54663, 690229
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q6RFH5, Q8VCG3
• Gene Symbols: WDR74
• Immunogen: An 18 amino acid peptide near the carboxy terminus of human NSA1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG