Invitrogen™ WDR59 Monoclonal Antibody (K16273_16H3), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA556211

Product Code. 30208694

Description

Sequence of this protein is as follows: RKQKEGSKDY QLVTWSRDQT LRMWRVDSQM QRLCANDILD GVDEFIESIS LLPEPEKTLH TEDTDHQHTA SHGEEEALKE DPPRNLLEER KSDQLGLPQT

As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210). [UniProt].

Specifications

• Antigen: WDR59
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
• Gene Accession No.: Q6PJI9
• Gene Symbols: WDR59
• Immunogen: Recombinant human WDR59 (immunogen range is 291-390).
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot
• Clone: K16273_16H3
• Conjugate: Unconjugated
• Gene: WDR59
• Gene Alias: FP977; GATOR complex protein WDR59; KIAA1923; WD repeat domain 59; WD repeat-containing protein 59; WDR59
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 79726
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid