Invitrogen™ WDR5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA585665

Product Code. 16372595

Description

Keep as concentrated solution. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (80%), Chimpanzee (100%), Bovine (97%). Positive Control: Neuro2A, C8D30, NIH-3T3, Raw264.7, C2C12, HepG2, HepG2 nuclear fraction extract, PC-12, Rat-2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.

Specifications

• Antigen: WDR5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WDR5
• Gene Alias: 2410008O07Rik; AA408785; AA960360; Big; BIG3; BIG-3; BMP2-induced 3-kb gene protein; CFAP89; cilia and flagella associated protein 89; SWD3; SWD3, Set1c WD40 repeat protein, homolog; Unknown (protein for MGC:137327); WD repeat domain 5; WD repeat-containing protein 5; WD repeat-containing protein BIG-3; Wdr5; wu:fk47f04; zgc:56591; zgc:76895; zgc:76895 protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11091, 140858, 362093
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.67 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P61964, P61965, Q498M4
• Gene Symbols: WDR5
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human WDR5. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG