Invitrogen™ WDR45 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA577801

Product Code. 16376514

Description

A 1:1,000 dilution of PA5-77801 was sufficient for detection of WIPI4 in 15 μg of Human HeLa Cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody. Detects approximately 40 kDa.

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined.

Specifications

• Antigen: WDR45
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WDR45
• Gene Alias: JM5; NBIA4; NBIA5; neurodegeneration with brain iron accumulation 4; neurodegeneration with brain iron accumulation 5; WD repeat domain 45; WD repeat domain phosphoinositide-interacting protein 4; WD repeat domain, X-linked 1; WD repeat-containing protein 45; WD45 repeat protein interacting with phosphoinositides 4; WDR45; WDRX1; WDRXI4; WIPI4; WIPI-4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11152, 302559
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q5U2Y0, Q9Y484
• Gene Symbols: WDR45
• Immunogen: Synthetic peptide from the C-terminal of Human WIPI4 (aa 312-322).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG