Invitrogen™ WDR4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5112269

Product Code. 17110134

Description

WDR4 Polyclonal Antibody for Western Blot, IHC (P), IP

Required for 7-methylguanosine modification of tRNA. This protein is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD). which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes. including cell cycle progression. signal transduction. apoptosis. and gene regulation. This protein is excluded as a candidate for a form of nonsyndromic deafness (DFNB10). but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternative splicing of this gene generates at least 3 transcript variants. two of which diverge at the 3' UTR and thus encode the same protein products.

Specifications

• Antigen: WDR4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WDR4
• Gene Alias: AI415180; AI448349; D530049K22Rik; hWH; mWH; Protein Wuho homolog; TRM82; TRM82 tRNA methyltransferase 82 homolog; TRMT82; tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; tRNA (guanine-N(7)-)-methyltransferase subunit WDR4; WD repeat domain 4; WD repeat-containing protein 4; WD40 repeat protein 4; WDR4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 10785
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.03% ProClin 300; pH 7
• Gene Accession No.: P57081
• Gene Symbols: WDR4
• Immunogen: E. coli-derived Human WDR4 fragment.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG