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VU0364770, MedChemExpress

Product Code. p-200097571
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Product Code. 16484386

Brand: Medchem Express HY100588

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Description

MedChemExpress VU0364770 is a selective and potent positive allosteric modulator (PAM) of mGlu4.

VU0346770 exhibits EC50s of 290 nM and 1.1 μM at rat mGlu4 and human mGlu4 receptor, respectively. VU0364770 exhibits antagonist activity at mGlu5 with a potency of 17.9 μM and PAM activity at mGlu6 with a potency of 6.8 μM. VU0364770 also possesses activity at MAO with Ki values of 8.5 and 0.72 μM for human MAO-A and human MAO-B, respectively.

Specifications

Chemical Name or Material VU0364770
CAS 61350-00-3
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C12H9ClN2O
Quantity 100 mg
Solubility Information DMSO : ≥ 100 mg/mL (429.79 mM)
SMILES O=C(C1=NC=CC=C1)NC2=CC=CC(Cl)=C2
Molecular Weight (g/mol) 232.67
Formula Weight 232.67
Percent Purity 99.57%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neuromodulation
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Research purposes only

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