Invitrogen™ VPS8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA569218

Product Code. 15807633

Description

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:25266290). Functions predominantly in APPL1-containing endosomes (PubMed:25266290). [UniProt].

Specifications

• Antigen: VPS8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: VPS8
• Gene Alias: AI315068; AU040738; im:7166005; KIAA0804; mKIAA0804; RGD1309443; si:dkey-24b15.1; vacuolar protein sorting 8 homolog; vacuolar protein sorting 8 homolog (S. cerevisiae); vacuolar protein sorting-associated protein 8 homolog; VPS8; VPS8 CORVET complex subunit; VPS8 subunit of CORVET complex; VPS8, CORVET complex subunit; zgc:158695
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23355
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8N3P4
• Gene Symbols: VPS8
• Immunogen: synthetic peptide directed towards the N-terminal region of human VPS8.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG