Invitrogen™ VPS4B Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA530316

Product Code. 13484807

Description

Recommended positive controls: 293T. Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (88%), Xenopus laevis (88%), Chicken (89%), Rhesus Monkey (99%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16.

Specifications

• Antigen: VPS4B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: VPS4B
• Gene Alias: 8030489C12Rik; cell migration-inducing 1; cell migration-inducing gene 1 protein; MIG1; Protein SKD1; SKD1; SKD1B; Suppressor of K(+) transport growth defect 1; suppressor of K+ transport defect 1; vacuolar protein sorting 4 homolog B; vacuolar protein sorting 4 homolog B (S. cerevisiae); vacuolar protein sorting 4B; vacuolar protein sorting 4b (yeast); vacuolar protein sorting-associated protein 4B; VPS42; VPS4-2; Vps4b
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9525
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.32 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: O75351
• Gene Symbols: VPS4B
• Immunogen: Recombinant protein encompassing a sequence within the center region of human VPS4B. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG