Invitrogen™ VPS4A Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA534846

Product Code. 15388871

Description

Recommended positive controls: MCF-7. Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (90%), Xenopus laevis (92%), Pig (96%), Rhesus Monkey (100%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16; the gene for the other resides on chromosome 18.

Specifications

• Antigen: VPS4A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: VPS4A
• Gene Alias: 4930589C15Rik; AI325971; AW553189; hVPS4; Protein SKD2; SKD1; SKD1A; SKD1-homolog; SKD2; vacuolar protein sorting 4 homolog A; vacuolar protein sorting 4 homolog A (S. cerevisiae); vacuolar protein sorting 4a; vacuolar protein sorting 4a (yeast); vacuolar protein sorting factor 4A; vacuolar protein sorting protein 4a; vacuolar protein sorting-associated protein 4A; vacuolar sorting protein 4; VPS4; VPS4-1; VPS4A; vps4-A
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27183
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9UN37
• Gene Symbols: VPS4A
• Immunogen: Recombinant protein encompassing a sequence within the center region of human VPS4A. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG