Invitrogen™ VPS35 Monoclonal Antibody (10A8), FITC

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA545946

Product Code. 17817932

Description

A 1:1,000 dilution of MA5-45946 was sufficient for detection of VPS35 in 10 μg of SH-SY5Y by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody. Detects approximately 92 kDa.

This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex.

Specifications

• Antigen: VPS35
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS, 9.1mM sodium bicarbonate with 640.91mM DMSO, 136.36mM ethanolamine and no preservative; pH 7.4
• Gene Accession No.: Q96QK1, Q9EQH3
• Gene Symbols: VPS35
• Immunogen: Full length recombinant human VSP35.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 10A8
• Conjugate: FITC
• Gene: VPS35
• Gene Alias: AI647796; DKFZp434E1211; DKFZp434P1672; FLJ10752; FLJ13588; FLJ20388; hVPS35; Maternal embryonic message 3; maternal-embryonic 3; Mem3; PARK17; TCCCTA00141; vacuolar protein sorting 35; vacuolar protein sorting 35 homolog; vacuolar protein sorting 35 homolog (S. cerevisiae); vacuolar protein sorting-associated protein 35; Vesicle protein sorting 35; VPS35; VPS35 retromer complex component
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 25479, 55737, 65114
• Content And Storage: 4°C, store in dark
• Form: Liquid