Invitrogen™ VPS33B Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA529139

Product Code. 13413267

Description

Recommended positive controls: 293T, A431, HeLa, HepG2. Predicted reactivity: Mouse (99%), Rat (98%), Chicken (90%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.

Specifications

• Antigen: VPS33B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: VPS33B
• Gene Alias: FLJ14848; hVPS33B; r-vps33b; vacuolar protein sorting 33 homolog B; vacuolar protein sorting 33 homolog B (yeast); vacuolar protein sorting 33B; vacuolar protein sorting 33B (yeast); vacuolar protein sorting 33-like protein B; vacuolar protein sorting homolog r-vps33b; vacuolar protein sorting-associated protein 33B; vacuolar sorting protein 33b; vps33b; VPS33B late endosome and lysosome associated; VPS33B, late endosome and lysosome associated; zgc:110803
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 233405, 26276
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.97 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P59016, Q9H267
• Gene Symbols: VPS33B
• Immunogen: Recombinant protein encompassing a sequence within the center region of human VPS33B. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG