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Vorinostat, MedChemExpress

Product Code. 16499845
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Product Code. 16499845 Supplier Medchem Express Supplier No. HY10221

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Description

MedChemExpress Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC6 and HDAC7 (Class II) and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis. Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification.

Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC6 and HDAC7 (Class II) and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis. Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification.

Specifications

Chemical Name or Material Vorinostat
Physical Form Solid
CAS 149647-78-9
Color White
Quantity 250 mg
Purity Grade Notes Research
Molecular Formula C14H20N2O3
For Use With (Application) Cancer-programmed cell death
Synonym SAHA Suberoylanilide hydroxamic acid
Solubility Information DMSO : ≥ 100 mg/mL (378.33 mM)
SMILES O=C(NC1=CC=CC=C1)CCCCCCC(NO)=O
Molecular Weight (g/mol) 264.32
Formula Weight 264.32
Percent Purity 95.0%
Grade Research
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Research purposes only

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