Von Willebrand Factor Antibody (3E2D10 + VWF635), Novus Biologicals™

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
18175532	Novus Biologicals NBP2-34310-0.02MG	0.02 mg
18177042	Novus Biologicals NBP2-34310-0.1MG	0.1 mg

Description

Von Willebrand Factor Monoclonal specifically detects Von Willebrand Factor in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Von Willebrand Factor
• Dilution: Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human
• Gene Accession No.: P04275
• Gene ID (Entrez): 7450
• Immunogen: Recombinant human vWF fragment (3E2D10 & VWF635)
• Primary or Secondary: Primary
• Content And Storage: Store at 4C.
• Molecular Weight of Antigen: 250 kDa

• Clone: 3E2D10 + VWF635
• Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Cancer
• Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
• Gene Alias: coagulation factor VIII VWF, F8, F8VWF, von Willebrand factor, VWD, vWF
• Gene Symbols: VWF
• Isotype: IgG
• Purification Method: Protein A purified
• Test Specificity: Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.